Clin2
NCT07253129Possibly a fitRecruiting

Stem cell transplant study for T-cell lymphoma patients with partial response

Peripheral T Cell Lymphoma

Part of Blood & lymphatic, Cancer, Immune system & allergy clinical trials.

This study compares two types of stem cell transplants (from a donor or your own cells) for people with certain T-cell lymphomas who had only a partial response to first chemotherapy. It aims to see which approach may work better.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
88 people
Ages
18 years to 70 years
Study type
Observational

Who can take part

  • You are between 18 and 70 years old.
  • You have been diagnosed with one of these T-cell lymphomas: PTCL-NOS, ALK-negative ALCL, or follicular helper T-cell lymphoma.
  • You completed 6 cycles of chemotherapy (like CHOP) and your lymphoma shrank but didn't disappear (partial response).
  • You are healthy enough for a stem cell transplant, with good heart, lung, liver, and kidney function.
  • If you need a donor transplant, you have a matched related (at least 5/10) or unrelated (at least 8/10) donor.
  • You have not had prior treatment with a PD-1 inhibitor drug.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07353840Recruiting
Personalized treatment for T-cell lymphoma after first complete remission

This trial tests if giving a tailored treatment after first complete remission can improve outcomes for certain types of peripheral T-cell lymphoma. It is for people who have finished initial standard chemotherapy with a complete response.

Shanghai, Shanghai Municipality
NCT07470996Recruiting
T-cell lymphoma treatment after first therapy fails

This trial is for people with certain T-cell lymphomas that did not respond or got worse after initial chemotherapy. It offers a personalized treatment plan, possibly including a stem cell transplant, based on how your disease behaved after first-line therapy.

Shanghai, Shanghai Municipality
NCT07389616Recruiting· Phase 2/Phase 3
Preventing lymphoma return after transplant

This trial tests a combination of two drugs (cidabenamine and azacitidine) to help prevent peripheral T-cell lymphoma from coming back after a donor stem cell transplant. It is for patients who are at high risk of progression and have already had a transplant.

Shanghai, Shanghai Municipality
NCT05444712Recruiting
Stem cell transplant after best response in some T-cell lymphomas

This trial studies whether doing an autologous stem cell transplant (using your own stem cells) after a complete response helps people with certain T-cell lymphomas stay in remission longer. It may be an option if your lymphoma has shrunk completely and you fit the safety and testing requirements.

Amiens
NCT06724237Recruiting· Phase 3
High-dose chemo and stem cell transplant for T-cell lymphoma patients in remission

This trial tests whether high-dose chemotherapy followed by a stem cell transplant using your own cells can help people with certain types of peripheral T-cell lymphoma live longer. You would qualify if you have already finished your first round of chemotherapy and are in complete remission.

Birmingham, Alabama
NCT06741813Not yet recruiting
Comparing two stem cell transplants for adult T-cell lymphoma

This trial compares two types of stem cell transplants for adults with T-cell lymphoblastic lymphoma that has spread (stage III or IV) and has gone into remission after 3 rounds of chemo. The goal is to see which transplant approach works better.

Hear when a new Peripheral T Cell Lymphoma trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.