Clin2
NCT07031778Possibly a fitRecruiting

Topical simvastatin to help jawbone healing after wisdom tooth removal

Dimensional ChangesBone Density

Treatments studied

Part of Bones, joints & muscles clinical trials.

This study tests whether a simvastatin (a common cholesterol medicine) applied directly to the tooth socket after wisdom tooth removal can help your jawbone heal faster. If you need a lower wisdom tooth taken out and are generally healthy, you may be able to join.

Summary written for real people, not researchers, by Clin2.

Phase
Early Phase 1
Enrollment
90 people
Ages
18 years to 40 years
Study type
Interventional

Who can take part

  • You are scheduled to have a lower wisdom tooth (on the left side, tooth 37 or 47) removed.
  • Your wisdom tooth is either still under the gum (impacted) or only partly visible.
  • You are in good general health (classified as ASA I or II by your doctor).
  • You are not pregnant, not nursing, and not a daily smoker.
  • You are not taking statins for high cholesterol and do not have a bone disease or recent jaw radiation.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06664060Not yet recruiting· Early Phase 1
New bone implant for wisdom tooth healing

This trial tests a new bone implant to help wisdom tooth sockets heal better. You may be eligible if you need both lower wisdom teeth removed and are in good health.

NCT06879171Not yet recruiting
Alveolar ridge preservation with tooth graft and simvastatin

This study tests whether adding simvastatin (a common cholesterol drug) to a tooth graft helps preserve the jawbone after a tooth extraction. It might improve bone healing for people who need a dental implant later.

NCT07779421Recruiting
Healing bone after wisdom tooth removal

This study tests whether using a patient's own blood products can help bone heal better after removing a wisdom tooth. It may help reduce the gap left behind and protect the nearby molar.

Fuzhou, Fujian
NCT07086859Not yet recruiting
Preserving jawbone after tooth extraction with metformin

This study tests whether placing a small amount of metformin with your own tooth graft can help preserve the jawbone where a non-molar tooth is removed, especially if the socket has lost more than half of its outer bone wall. The goal is to improve the site for future dental implants.

Giza
NCT06141239Recruiting
3D imaging to study bone healing after tooth extraction

This trial uses advanced 3D imaging to measure how well your jawbone heals after a tooth is removed, specifically for people who plan to get a dental implant later. It aims to understand natural bone regrowth without additional procedures.

Taoyuan
NCT06935747Not yet recruiting· Phase 4
Bone healing after wisdom tooth removal using a special bone filler

This trial tests a special bone filler (beta-tricalcium phosphate) placed in the socket after impacted lower wisdom teeth are removed. The goal is to see if it helps the bone heal better than not using it.

Santiago de Compostela, A Coruña

Hear when a new Dimensional Changes trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.