Stem cell therapy for ankylosing spondylitis inflammation
Part of Bones, joints & muscles clinical trials.
This trial tests whether stem cells from donated bone marrow can reduce inflammation and pain in ankylosing spondylitis, a condition that causes the spine to become stiff and inflamed. Researchers will monitor how safe and effective this treatment is for eligible patients.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have been diagnosed with ankylosing spondylitis (a disease causing spine inflammation and stiffness)
- You are between 18 and 40 years old
- Your disease activity is moderate to high (measured by specific pain and inflammation scores)
- You have not used biologic drugs (like TNF inhibitors) in the past 6 months
- You do not have serious infections, cancer, heart disease, kidney disease, or other major health conditions
- You are able to follow study instructions and provide informed consent
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This trial tests whether stem cells from umbilical cord can reduce pain and stiffness in people with ankylosing spondylitis (a disease causing spinal inflammation). You may qualify if you have active AS that hasn't responded well to standard treatments.
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This study tests whether combining two types of immune-blocking drugs (an IL-17 inhibitor and a TNF inhibitor) works better than either alone for treating ankylosing spondylitis. It is for people whose symptoms are not well controlled with NSAIDs.
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