Light therapy and clobetasol for oral lichen planus
Part of Mouth & dental, Skin clinical trials.
This trial tests two light-based treatments (photobiomodulation and photodynamic therapy) and a steroid cream (clobetasol) for painful oral lichen planus. The goal is to see which treatment works best to reduce mouth sores and discomfort.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 20 and 70 years old.
- You have a confirmed diagnosis of oral lichen planus with sores or ulcers (from a biopsy).
- You have not had any treatment for oral lichen planus in the last 3 months.
- You do not have an active infection in your mouth (bacterial or fungal).
- You are not pregnant, breastfeeding, or planning to become pregnant (including 6 months after breastfeeding).
- You do not smoke more than 5 cigarettes per day.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a new sticky mouth film that slowly releases medicine to treat painful sores from oral lichen planus. It may help people who have not been treated before for this condition.
This trial tests whether a pineapple enzyme (bromelain) works as well as a standard steroid treatment for painful mouth sores caused by oral lichen planus. If you have this condition and are not taking other medications, you may be eligible.
This study tests whether treating gum disease along with using a steroid mouthwash or paste (a common treatment for lichen planus) helps heal mouth sores and reduce pain. It may be a good option if you have both oral lichen planus and gum disease.
This trial tests if a curcumin nanogel can help heal painful sores from oral lichen planus compared to a standard corticosteroid gel. If you have this condition, you may be able to join.
This trial tests a low-cost light therapy to treat precancerous mouth lesions (moderate to severe dysplasia or carcinoma in situ) that are at least 10 mm. The treatment uses a special light to destroy abnormal cells, possibly avoiding surgery.
This trial tests a mouthwash for oral lichen planus, a chronic condition causing painful sores in the mouth. The mouthwash contains hyaluronic acid and a peptide that may help reduce pain and irritation. If it works, it could offer a new treatment option.
Hear when a new Oral Lichen Planus trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.