Pain relief after root canal: piroxicam vs prednisolone
Treatments studied
Part of Mouth & dental, Pain clinical trials.
This trial compares a single dose of piroxicam (an NSAID) or prednisolone (a steroid) to see which one better reduces pain after a root canal in premolars. It may help choose the best pre-treatment for pain.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 40 years old and generally healthy
- You need a root canal on a premolar tooth that has painful, inflamed pulp (symptomatic irreversible pulpitis)
- The tooth’s root is fully developed as seen on an x-ray
- You are not pregnant and not taking pain or anti-inflammatory drugs now
- You aren’t allergic to lidocaine, piroxicam, or prednisolone
- The tooth can be restored and has no deep gum pockets or previous root canal treatment
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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