Pain relief medicines for root canal pain
Treatments studied
Part of Mouth & dental, Pain clinical trials.
This study compares two different pre-medications (piroxicam and prednisolone) to see which one better reduces pain after a single-visit root canal on a premolar. If you are having a root canal for a painful premolar, this trial may help manage your post-treatment pain.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 40 years old.
- You need root canal treatment on a premolar (the tooth in front of your molars) because the nerve inside the tooth is inflamed and causing severe pain.
- The tooth must be fully formed (grown in completely) as seen on an X-ray.
- You are generally healthy and do not have serious conditions like HIV or hepatitis.
- You are not pregnant.
- You have not taken painkillers or anti-inflammatory medications recently.
- You are not allergic to the local anesthetic (lignocaine) or the study medicines (piroxicam and prednisolone).
- The tooth can be restored (filled) and does not have severe gum disease or a blocked root canal.
- This is your first root canal treatment on that tooth.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study compares two types of medications placed inside a tooth after root canal treatment to see which one reduces pain better. You'll be asked about your pain levels after treatment, and researchers will measure a pain-related substance in your saliva.
This study compares two types of medication placed inside the tooth during a root canal to see which works better for pain and fighting infection. It may help you feel more comfortable and improve the success of your root canal treatment.
This study compares three different pain relievers to see which works best for pain after a single-visit root canal. It may help find better ways to manage post-procedure discomfort.
This study tests two methods to lessen pain after a root canal: using sound waves to clean the tooth and applying cold inside the tooth. It aims to see which method works better for reducing discomfort.
This study tests if taking a dose of diclofenac potassium, a common pain reliever, before a root canal reduces pain afterward. It may help people with severe tooth pain feel better during and after treatment.
This study tests whether taking ibuprofen or dexamethasone before a root canal can help reduce pain afterward. It's for people with a painful, inflamed tooth nerve who haven't already taken pain medicine for it.
Hear when a new Irreversible Pulpitis with Apical Periodontitis trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.