Darolutamide plus hormone therapy after prostate removal
Treatments studied
Part of Cancer, Kidney & urinary clinical trials.
This trial tests a combination of darolutamide (a pill that blocks male hormones) and standard hormone therapy (ADT) for men with high-risk prostate cancer that has not spread beyond the pelvis, after their prostate has been removed. The goal is to see if this treatment can help prevent the cancer from coming back.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are a man between 18 and 75 years old.
- Your prostate cancer was confirmed by biopsy and is considered high-risk based on a specific risk calculator (Briganti 2019 nomogram).
- You had your prostate removed (radical prostatectomy) but did not have lymph nodes removed from the pelvis.
- Your PSA level was less than 0.1 ng/mL at 6 weeks after surgery.
- You are not getting radiation therapy after surgery, or you have chosen not to have it.
- You have not had more than 2 months of hormone therapy, or any chemotherapy, immunotherapy, or targeted therapy for your prostate cancer.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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