Study of sarilumab for early polymyalgia rheumatica
Treatments studied
Part of Bones, joints & muscles, Skin clinical trials.
This trial tests whether the drug sarilumab can help people with newly diagnosed or early relapsing polymyalgia rheumatica (PMR) reduce their need for prednisone. It aims to see if the combination is safer and more effective than prednisone alone.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 50 years old or older and have been diagnosed with polymyalgia rheumatica (PMR).
- If newly diagnosed, you have been on corticosteroids for 6 weeks or less. If you have had a flare, you must have been on at least 10 mg of prednisone daily for 8 weeks and had a flare in the last 12 weeks while on at least 5 mg daily.
- You are willing and able to take 15 mg of prednisone daily at the start of the study.
- You do not have giant cell arteritis, rheumatoid arthritis, other inflammatory joint diseases, or connective tissue disorders.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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Other trials that look related to this one.
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This trial tests if new imaging methods can help diagnose and treat polymyalgia rheumatica (PMR). It may be for you if you're over 50, have pain in your shoulders or hips, and haven't taken steroids for PMR in the last 2 months.
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