N-acetylcysteine for airway clearance in bronchiectasis
Part of Lungs & breathing clinical trials.
This trial tests whether adding N-acetylcysteine (a medicine that thins mucus) to your usual hospital care helps clear your airways faster during a bronchiectasis flare-up. People in the hospital for a sudden worsening of their bronchiectasis may be eligible.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years old or older.
- You have been diagnosed with bronchiectasis (damaged, widened airways in the lungs).
- You are currently in the hospital because your bronchiectasis suddenly got worse (called an acute exacerbation).
- You do not currently smoke.
- You are not allergic to N-acetylcysteine (a medicine that helps thin mucus).
- If you are female, you are not pregnant or breastfeeding.
- You do not have COPD or asthma as your main lung condition.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests if washing the lungs with acetylcysteine (a mucus-thinning medicine) during a bronchoscopy can help people with bronchiectasis who are having a flare-up. The goal is to see if it improves symptoms like cough and mucus.
This study tests if giving antibiotics (levofloxacin or gentamicin) directly into the lungs during a bronchoscopy can help patients with bronchiectasis who are in the hospital with a sudden worsening of symptoms or are on a breathing machine.
This trial tests if breathing in a medication called acetylcysteine can help prevent lung infections in patients who are on a breathing machine. If you or a loved one is on a ventilator, this treatment might reduce the chance of getting ventilator-associated pneumonia.
This trial tests an inhaled medicine called H057 for people whose bronchiectasis symptoms (like cough, more phlegm, or shortness of breath) have suddenly gotten worse. The goal is to see if it can help control this worsening episode.
This trial tests whether inhaling a saltwater solution (hypertonic saline) twice a day for 12 weeks can help people with bronchiectasis who have a chronic cough and have had flare-ups in the past. It aims to see if this treatment reduces mucus and improves quality of life.
This trial tests a home-use device called BiWaze Clear, which helps clear mucus from your lungs. It is for people with bronchiectasis (including those with cystic fibrosis) who have had recent lung infections and can use the device at home.
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