Azithromycin to Reduce Bronchiectasis Flare-Ups
Treatments studied
Part of Lungs & breathing clinical trials.
This study tests whether a common antibiotic called azithromycin can help prevent flare-ups (sudden worsening) of bronchiectasis—a lung condition where airways become permanently enlarged and damaged. Patients will take azithromycin or a placebo for 12 months to see if it reduces how often they get sick.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have bronchiectasis (enlarged, damaged airways) that is not caused by cystic fibrosis
- You are 18 years or older
- You can commit to visiting the clinic regularly for 12 months of follow-up visits
- You have no serious heart problems that would make the antibiotic unsafe
- You are not currently using other long-term macrolide antibiotics (like azithromycin, clarithromycin, or erythromycin)
- You do not have active tuberculosis or other serious infections requiring treatment
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
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This study helps doctors understand how severe your bronchiectasis is and predict when you might have flare-ups. You'll have routine tests over 12 months to help researchers learn more about this condition and improve future care.
This study tests if giving antibiotics (levofloxacin or gentamicin) directly into the lungs during a bronchoscopy can help patients with bronchiectasis who are in the hospital with a sudden worsening of symptoms or are on a breathing machine.
This trial tests whether giving a low dose of azithromycin (an antibiotic) can prevent lung infections in young children with structural lung damage or congenital lung/airway malformations. The goal is to reduce infections and keep lungs healthier.
This study tests whether placing a common antibiotic (amikacin) directly into the lungs during a bronchoscopy helps people with bronchiectasis recover faster from sudden flare-ups. Participation involves a bronchoscopy and a lung rinse, which may reduce infection and improve breathing.
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This study looks at how bacteria live in the lungs of people with bronchiectasis and how they may adapt over time. It may help researchers understand why infections keep coming back and how to better manage chronic lung colonization.
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