Clin2
NCT07295314Possibly a fitNot yet recruiting

Antifungal medicines and their effect on gut bacteria

Gut MicrobiomeHealthy Adult MaleAntifungal Therapy

Treatments studied

Part of Digestive system clinical trials.

This study tests whether a short course of antifungal medicines changes the natural bacteria in your gut. It is a small early study, so the main goal is to see if the drug has an effect and if it's safe, which could one day help treat gut-related conditions.

Summary written for real people, not researchers, by Clin2.

Phase
Early Phase 1
Enrollment
50 people
Ages
18 years to 35 years
Study type
Interventional

Who can take part

  • You are a man between 18 and 35 years old.
  • You are generally healthy, with no major illnesses in the past 3 months and no long-term health problems.
  • You have a normal bathroom routine (between 3 times a week and 3 times a day).
  • You have no current or past gut diseases like Crohn's disease or ulcerative colitis.
  • You have not taken antibiotics or antifungals (by mouth or injection) in the last 3 months, and you haven't taken other medications or supplements recently.
  • You don't drink more than 3 alcoholic drinks per day on average, and you have no allergy to antifungal medications.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06433310Recruiting· Phase 4
A dietary supplement's effect on gut fungi in healthy adults

This study tests whether a dietary supplement (L-phenylalanine) can affect the natural balance of fungi in the gut. Healthy volunteers take the supplement for a short time, and researchers check how it changes their gut fungi.

New York, New York
NCT07300553Recruiting· Phase 2
Gut bacteria and energy metabolism in health and IBD

This study looks at how the bacteria living in your gut affect your body's energy use. It includes both healthy volunteers and people with inactive Crohn's disease or ulcerative colitis.

Paris
NCT06819410Recruiting
Comparing antifungal treatments for invasive fungal disease

This trial studies two types of antifungal medicines (amphotericin B and azoles) to see which works better for people with invasive fungal disease. It aims to help doctors choose the safest and most effective treatment.

Chengdu, Sichuan
NCT03437005Recruiting· Phase 1
Testing how common skin creams change gut microbes

This study looks at whether commonly used topical (skin) medications change your skin and gut microbial “ecosystem.” It’s an early (Phase 1) pilot study, mainly to see how these treatments affect samples over time.

Sacramento, California
NCT06969703Not yet recruiting
Fungal infection treatment and resistance study

This study looks at how well antifungal medicines work against different fungi and how fungi become resistant. By joining, you may help doctors understand your infection and improve future treatments.

Beijing
NCT07649096Not yet recruiting· Phase 1
Testing a yeast-based treatment for C. diff infections

This trial tests a new medicine made from a weakened yeast that is designed to fight a bacteria called C. diff, which can cause severe diarrhea. It's a first-in-human safety study, so the main goal is to see if the medicine is safe and how your body handles it.

Hear when a new Gut Microbiome trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.