Comparing biopsy methods for prostate cancer detection
Part of Cancer, Kidney & urinary clinical trials.
This trial is testing whether taking extra biopsy samples from specific areas seen on an MRI can better detect prostate cancer compared to the standard method of taking samples from all over the prostate. It may help men who have a suspicious MRI finding and a higher PSA level.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are an adult man, 18 years or older.
- Your doctor suspects you might have prostate cancer based on tests like a rectal exam, family history, or PSA levels, and has recommended a prostate biopsy.
- You have had a special MRI scan (multiparametric MRI) showing a suspicious area rated PI-RADS 4 or 5, or a PI-RADS 3 area with a PSA density of 0.15 or higher.
- You are healthy enough to have a prostate biopsy with local or general anesthesia.
- Your PSA level is 20 ng/mL or lower.
- You have not been diagnosed with prostate cancer before and have never had a negative prostate biopsy.
- You understand the study and agree to take part by signing a consent form.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study compares how well a doctor’s MRI reading (the PI-RADS score) and a computer AI tool detect prostate cancer. It may help improve how men get targeted biopsies and avoid missing important cancers.
This study tests if a special MRI measurement (ADC) can improve how well a standard MRI finds prostate cancer. If you have a suspicious MRI and are scheduled for a biopsy, this might help better understand your results.
This study is testing a new approach to prostate biopsy that takes samples from around a suspicious area seen on MRI. It aims to see if this method can better detect prostate cancer compared to standard biopsy.
This study uses repeat MRI scans to monitor men with an intermediate suspicion of prostate cancer, aiming to reduce unnecessary biopsies while still catching significant cancers early.
This trial compares two ways to guide a prostate biopsy using MRI images, to see which better detects clinically significant prostate cancer in men with suspicious MRI findings.
This trial studies special MRI images to learn how well they can find prostate cancer before treatment. It may help doctors choose better next steps during biopsy or during active surveillance.
Hear when a new Prostate cancer trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.