Semaglutide for weight loss in teens with genetic obesity
Treatments studied
Part of Hormones & metabolism clinical trials.
This trial studies whether semaglutide (a once-weekly injection) helps adolescents with a specific genetic form of obesity lose weight. It is for teens who are already being prescribed semaglutide as part of their regular care.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 12 and 21 years old.
- You have a BMI at or above the 95th percentile for your age and sex (based on CDC growth charts).
- You weigh more than 60 kg (about 132 lbs).
- You have been diagnosed with monogenic obesity by a certified lab, meaning a specific gene change causes your obesity.
- You (and your parent or guardian) agree to take part in the study.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study looks at how semaglutide works in real life for people with obesity caused by a single gene change. If you or your teenager have this type of obesity and are taking or about to start semaglutide, you may be able to join.
This trial studies how the body adapts to weight loss in teens with obesity. You will either get a behavioral lifestyle program alone or with a weight loss medication called semaglutide.
This study tests whether semaglutide (a once-weekly injection that helps with weight loss) can help teenagers with autism who are obese. It will compare their results to similar teens who did not take the drug to see if it is safe and effective.
This study looks at how teenagers and young adults respond to weight-loss surgery (sleeve gastrectomy) and whether adding a medication called semaglutide can help improve weight loss. It has two parts: first observing how surgery affects you, then testing if semaglutide helps those who didn't lose enough weight after surgery.
This study tests a medication called semaglutide (which helps with weight loss) in people with obesity who have struggled to lose weight before. It will see how much weight participants can lose while taking the drug.
This study tests if a medication called semaglutide can help people with obesity lose weight by changing the bacteria in their gut. You may be able to join if you have obesity, have tried to lose weight before, and are generally healthy.
Hear when a new Monogenic Obesity trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.