Ketamine treatment study for severe major depression
Treatments studied
Part of Mental health clinical trials.
This study tests how a single dose of ketamine affects certain brain and body markers in people with severe depression. It aims to find better ways to predict who will respond to ketamine, which may help personalize depression treatment in the future.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be physically healthy and have a current major depressive episode due to major depressive disorder.
- Your depression must be severe enough, as measured by a standard scoring tool (score of at least 22).
- If you take antidepressants, your dose must have been stable for at least 6 weeks.
- You cannot have a history of bipolar, schizophrenia, or other psychotic disorders.
- You cannot have received electroconvulsive therapy (ECT) in the last 3 months.
- You cannot have a history of IV drug use or have failed ketamine treatment before.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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