ACE1831 for active lupus after standard treatments fail
Treatments studied
Part of Immune system & allergy, Skin clinical trials.
This study tests an investigational drug called ACE1831 for people with active systemic lupus erythematosus (lupus) whose disease has not improved with usual treatments. The goal is to see if ACE1831 can reduce lupus activity and help control symptoms.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 to 60 years old.
- You must have a confirmed lupus diagnosis (using standard criteria).
- Your lupus must be active and moderate to severe, with a score of 8 or more on the SLEDAI-2K scale.
- You must have tried and not responded well to corticosteroids and at least two other lupus treatments for at least 3 months.
- You must test positive for certain lupus antibodies (anti-dsDNA, ANA, or anti-Smith).
- If you can become pregnant, you must agree to use highly effective birth control during the study and for 1 year after treatment.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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