Clin2
NCT07322848Possibly a fitRecruiting

Comparing two TACE methods for liver cancer patients with TIPS

Hepatocellular Carcinoma (HCC)TACETIPSDEB-TACEcTACE

Part of Cancer, Digestive system clinical trials.

This trial tests whether a newer targeted chemotherapy bead method (DEB-TACE) works better than standard chemo beads (cTACE) for people with liver cancer who already have a TIPS shunt in place. It aims to find a treatment that controls tumors while being safe for patients with this shunt.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
206 people
Ages
18 years to 75 years
Study type
Interventional

Who can take part

  • You have liver cancer that is too large or has too many tumors for a liver transplant based on Milan criteria.
  • You have a TIPS shunt placed at least 1 month ago to treat bleeding or fluid buildup, and it is still working well.
  • Your liver function is good (Child-Pugh class A or B) and your lab results meet certain levels for blood cells, liver enzymes, and kidney function.
  • You have not had any cancer treatment in the last 12 months, and you have no other active cancers or serious infections.
  • You are not pregnant or planning pregnancy, and you do not have a history of brain metastases or allergies to contrast dye.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07293468Recruiting· Phase 2/Phase 3
Comparing two treatments for advanced liver cancer

This trial tests two different ways to treat liver cancer that can't be removed with surgery. It compares stereotactic body radiation therapy (targeted high-dose radiation) with selective internal radiation therapy (tiny radioactive beads delivered through a blood vessel), both combined with immunotherapy (medicines that help your immune system fight cancer).

Hong Kong
NCT07422753Recruiting· Phase 2
TACE with immunotherapy drugs for advanced liver cancer

This trial tests a combination of TACE (a procedure that blocks blood supply to the tumor) plus three immunotherapy drugs (sintilimab, bevacizumab, ipilimumab) for people with advanced liver cancer that cannot be removed by surgery. The goal is to see if this combination works better than TACE alone.

Hangzhou, Zhejiang
NCT07836309Not yet recruiting
Combining TACE with tislelizumab and lenvatinib for advanced liver cancer

This study looks at combining TACE (a procedure that delivers chemotherapy directly to the liver) with two newer drugs — tislelizumab (immunotherapy) and lenvatinib (targeted therapy) — for people with advanced liver cancer. The goal is to see how well this combination works when used together.

Nanjing, Jiangsu
NCT06876753Recruiting
Advanced liver cancer: TACE with immunotherapy and anti-angiogenesis

This trial is for people with advanced liver cancer (HCC) that has spread outside the liver. It tests whether combining a TACE procedure with immunotherapy and anti-angiogenesis drugs can improve outcomes. You must not have had prior systemic therapy and must have received TACE in a specific time window around starting these drugs.

Nanjing, Jiangsu
NCT07128251Not yet recruiting· Phase 2
TACE plus immunotherapy and bevacizumab for liver cancer

This study combines a liver-directed procedure called TACE (which blocks blood flow to the tumor and delivers chemotherapy directly to it) with two immunotherapy drugs and a targeted therapy (bevacizumab). The goal is to see if this combination can shrink liver cancer that cannot be surgically removed, without the cancer having spread elsewhere.

NCT05985798Recruiting· Phase 3
Immunotherapy plus TACE vs. Targeted Therapy plus TACE for Advanced Liver Cancer

This trial is testing a combination of two immunotherapy drugs (sintilimab and bevacizumab) plus a procedure called TACE (chemoembolization) against a targeted therapy pill (lenvatinib) plus TACE for people with advanced liver cancer. The goal is to see which approach works better to shrink tumors and improve outcomes.

Guangzhou, Guangdong

Hear when a new Hepatocellular Carcinoma (HCC) trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.