Clin2
NCT07324473Possibly a fitNot yet recruiting

Second-line treatment for advanced liver cancer after drug resistance

Hepatocellular CarcinomasResistance to ImmunotherapyImmunomodulationDrug Repurposing

Part of Cancer, Digestive system clinical trials.

This trial tests whether a combination of immunotherapy and targeted therapy can help people with advanced liver cancer whose first treatment stopped working. It aims to shrink tumors and slow the cancer's growth.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
65 people
Ages
18 years to 75 years
Study type
Interventional

Who can take part

  • You have advanced liver cancer (hepatocellular carcinoma) that cannot be removed with surgery.
  • Your cancer has grown after at least 4 cycles of a first-line treatment that combined targeted therapy and immunotherapy.
  • You have at least one tumor that can be measured on a scan (at least 10 mm across).
  • You are physically active enough to handle daily tasks (ECOG performance status 0 or 1).
  • Your liver, kidney, and blood function are within safe limits.
  • You have not had any other cancer in the last 5 years and do not have certain other liver cancer types.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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