New combination therapy for advanced liver cancer
Treatments studied
Part of Cancer, Digestive system clinical trials.
This trial tests a combination of treatments for advanced liver cancer: a targeted therapy (apatinib), an immunotherapy (camrelizumab), and two local treatments (TAE and HAIC). It may be an option if you have a high tumor burden or a tumor thrombus in the portal vein and haven't had systemic treatment before.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 80 years old.
- You have been diagnosed with hepatocellular carcinoma (a type of liver cancer) that has not spread to other parts of the body and is stage IIa to IIIb.
- You have not received any previous treatment that goes through your whole body (like chemotherapy, targeted therapy, or immunotherapy).
- You have a high tumor burden OR a tumor thrombus (cancer clot) in the main portal vein or its main branch.
- Your liver function is good (Child-Pugh class A or B) and you are in generally good health (ECOG score 0-1).
- If you have hepatitis B, your viral load is low (HBV-DNA ≤ 2000) or you are on antiviral medication.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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