Clin2
NCT07326124Possibly a fitNot yet recruiting

Cannabidiol for early psychosis not fully improved by clozapine

Treatment Resistant PsychosisPsychosis

Treatments studied

Part of Mental health clinical trials.

This trial tests whether adding a cannabis-based medicine called cannabidiol (CBD) to clozapine helps people with early psychosis who still have symptoms. It may improve your symptoms and overall well-being.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
250 people
Ages
16 years to 50 years
Study type
Interventional

Who can take part

  • You must be between 16 and 50 years old
  • You must have been taking clozapine for at least 8 weeks at a certain dose
  • You must have been on antipsychotic medication for less than 10 years
  • You must have symptoms like delusions, hallucinations, or disorganized thinking
  • You must be willing to use effective birth control if you could become pregnant
  • You must be able to attend all trial visits and follow the study plan

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06778564Recruiting· Phase 3
CBD (cannabidiol) for early psychosis

This study tests if adding a CBD medication to your current antipsychotic can improve symptoms in people with schizophrenia or related disorders who started treatment recently but aren't fully better yet.

Vienna
NCT07245212Not yet recruiting
Cannabis clinic support for first episode psychosis

This trial tests a special clinic that helps people with a first episode of psychosis cut down or stop using cannabis. The clinic provides talking support and practical help, and the goal is to improve your mental health and quality of life.

London
NCT04411225Recruiting· Phase 3
CBD may help early psychosis along with usual treatment

This Phase 3 trial tests whether taking cannabidiol (CBD) can reduce symptoms when added to standard care for early psychosis (like first-episode psychosis or attenuated psychosis). It may help some people have fewer troubling thoughts or perceptions over time.

La Jolla, California
NCT07434973Not yet recruiting· Phase 3
Cannabidiol for young people at high risk for psychosis

This study tests whether a medication called cannabidiol (a non-intoxicating compound from cannabis) can help reduce symptoms and prevent progression in young people at clinical high risk for psychosis. Participants will receive either the study drug or a placebo (a pill with no active ingredient) and will be followed to see how they respond.

Vienna
NCT05867849Recruiting· Phase 3
Cannabidiol treatment for bipolar depression symptoms

This trial tests whether cannabidiol (CBD) can reduce symptoms of bipolar depression. You may be eligible if you have bipolar I or II and a current depressive episode while staying on approved mood-stabilizing or antipsychotic medication.

Vancouver, British Columbia
NCT06569394Recruiting· Phase 2
Testing CBD in young adults who use cannabis heavily

This study tests whether cannabidiol (CBD) can help young adults who use cannabis heavily but aren't looking to quit. You'll take a CBD pill and see if it changes your cannabis use or related symptoms.

Aurora, Colorado

Hear when a new Psychosis trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.