Comparing two pills for moderate to severe psoriasis
Treatments studied
Part of Immune system & allergy, Skin clinical trials.
This trial tests two oral medications, Apremilast and Methotrexate, to see which works better for people with moderate to severe plaque psoriasis. You must not have taken systemic treatments (pills or shots that work throughout the body) in the last 3 months.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be between 18 and 60 years old.
- You must have moderate to severe plaque psoriasis, meaning a score of at least 10 on a standard severity scale (PASI).
- You cannot have taken any systemic psoriasis treatment (pills or injections) in the past 3 months.
- You cannot be pregnant, breastfeeding, or planning to become pregnant.
- You must not have a history of liver or kidney problems.
- You must not have a known allergy to Apremilast or Methotrexate.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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