Methotrexate vs tofacitinib pills for plaque psoriasis
Treatments studied
Part of Skin clinical trials.
This study compares two oral pill treatments—methotrexate and tofacitinib—for people with chronic plaque psoriasis that is moderate to severe and hasn't responded well to creams. The goal is to see which pill works better at clearing skin.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 70 years old.
- You have had chronic plaque psoriasis for at least 6 months.
- Your psoriasis is moderate to severe, covering 10% or more of your skin.
- Creams and ointments haven't worked well enough for your psoriasis.
- You have not used strong psoriasis medicines (like steroid pills or injections) in the last 4 weeks.
- You are not pregnant, breastfeeding, or planning to become pregnant during the study.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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