Xeligekimab for non-radiographic axial spondyloarthritis
Treatments studied
Part of Bones, joints & muscles clinical trials.
This trial tests a drug called Xeligekimab for people with a type of spinal arthritis that doesn't show up on X-rays but still causes symptoms. The goal is to see if the drug can reduce pain and inflammation and improve quality of life.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 or older.
- You have a type of spinal arthritis (non-radiographic axial spondyloarthritis) diagnosed by a rheumatologist.
- You have tried NSAID pain relievers (like ibuprofen or naproxen) and they didn't work well or you couldn't take them.
- You have signs of inflammation, such as an abnormal MRI or high C-reactive protein level.
- Your disease is active, with significant back pain and stiffness (BASDAI score of 4 or more).
- You must not have joint damage visible on X-rays (sacroiliitis) of a certain severity.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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