Testing a migraine trigger for people without aura
Treatments studied
Part of Brain & nervous system, Pain clinical trials.
This study looks at whether a natural substance called amylin can trigger migraine attacks in people who get migraines without aura. If you join, you'll receive an infusion and be monitored to see if you get a migraine, which could help researchers understand migraine causes.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 65 years old
- You weigh between 110 and 220 pounds (50 to 100 kg)
- You have had migraines without aura for at least a year, with 1 to 5 such migraines per month on average
- You do not have other headache disorders, heart or lung disease, or a history of moderate to severe head injury
- You are not taking daily medications (except contraceptives) and can avoid caffeine, nicotine, alcohol, and pain relievers for a short time before the study
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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