Testing a new drug target for migraine relief
Part of Brain & nervous system, Pain clinical trials.
This trial tests a substance that activates adrenomedullin receptors, which may be a new way to treat migraines. It may help people who have migraines without aura and aren't on preventive migraine medications.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years old or older.
- You have had migraines without aura for at least 1 year.
- You currently have 1 to 5 migraine attacks per month.
- You have not taken any preventive migraine medication in the last 30 days.
- You have never used treatments that target CGRP (like certain antibody injections or pills).
- You are not pregnant, breastfeeding, or planning to become pregnant.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study looks at whether a natural substance called amylin can trigger migraine attacks in people who get migraines without aura. If you join, you'll receive an infusion and be monitored to see if you get a migraine, which could help researchers understand migraine causes.
This study tests new ways to monitor how well preventive migraine treatments are working. It is for people with chronic migraine who may be starting or already using preventive medications.
This study tests an investigational medication called NB001 for treating migraine attacks as they happen. If you have frequent migraines, this treatment might help reduce the severity or shorten the duration of your attacks.
This trial tests a new medicine, MEDI0618, against a placebo for people with episodic migraine. The goal is to see if MEDI0618 is safe and effective at reducing migraine days.
This study tests a new inhaled powder form of a migraine medication called dihydroergotamine (DHE) to see if it safely and effectively stops migraine attacks. If you have frequent migraines, this trial might offer you a new treatment option to try.
This study looks at blood samples from people with migraine to find proteins and other markers that might explain why migraines happen. The goal is to better understand migraine, which could help find better treatments in the future.
Hear when a new Migraine trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.