How other medicines affect a new drug in healthy people
Treatments studied
This study tests a new drug (clifutinib) in healthy volunteers to see how other common medicines (itraconazole, fluconazole, and efavirenz) affect its levels in the body. The results will help doctors understand how to dose clifutinib in future patients.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be between 18 and 50 years old.
- Your body mass index (BMI) must be between 18 and 28. (BMI is a measure of body fat based on height and weight.)
- You must not be pregnant or breastfeeding, and you must agree to use effective birth control for 6 months after the study.
- You must be generally healthy, with no major medical conditions like heart, liver, or kidney disease.
- You cannot be taking any prescription or over-the-counter medicines, vitamins, or herbal supplements for at least 14 days before the study starts.
- You must be willing to avoid smoking, alcohol, caffeine, and certain foods (like grapefruit) during the study.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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