Triggering migraine with aura using a study drug
Part of Brain & nervous system clinical trials.
This study tests whether giving a substance called PACAP38 can trigger a migraine with aura in a controlled setting. It helps understand the causes of migraines and may lead to better treatments.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be between 18 and 65 years old.
- You must have had migraine with aura for at least 12 months.
- On average, you should have at least 1 day per month with aura symptoms in the 3 months before screening.
- You cannot have any other headache disorder except certain types (migraine without aura, chronic migraine, or tension headaches).
- You must not have heart disease, high or low blood pressure problems (check with your doctor).
- You cannot have had a headache, aura, or taken acute migraine medication (like painkillers or triptans) within 48 hours before the study infusion.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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