Studying a new heart valve replacement system for aortic stenosis
Part of Heart & circulation clinical trials.
This trial is testing a new heart valve system (Medtronic Evolut FX+) for people with severe aortic stenosis—a condition where the heart's main valve is narrowed. The study aims to see how well the valve works and improve your care journey.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older and can give written consent.
- You have severe aortic stenosis that causes symptoms like shortness of breath, chest pain, or fainting.
- You do not have a previously implanted surgical heart valve.
- Your liver function is not severely impaired (no advanced liver disease).
- Your doctor has determined the Evolut FX+ system is suitable for your heart's anatomy.
- You are not in another study that could affect this one.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study is tracking how well the Myval valve works in people with severe aortic stenosis who get it through a minimally invasive procedure called TAVI. It helps doctors learn more about the valve's safety and performance in real-world use.
This trial compares two newer types of replacement heart valves (SAPIEN 3 Ultra Resilia and Evolut FX) to see which one works better for people with severe aortic stenosis, a condition where the heart's main valve becomes narrow. If you join, you'll be randomly assigned to receive one of the two valves during your TAVI procedure.
This study is looking at how well doctors can reach the coronary arteries (the blood vessels that supply the heart muscle) after a TAVI procedure using the Evolut FX Plus valve. It may help improve future procedures for people with severe aortic stenosis.
This trial tests a new valve device placed through a small tube (catheter) to treat severe aortic stenosis, a condition where the aortic valve is narrowed and doesn't open fully. It's for patients who cannot have traditional open-heart surgery.
This trial is testing a new, less invasive way to replace a narrowed aortic valve using a special device. The goal is to help improve blood flow and reduce symptoms like chest pain and shortness of breath.
This trial tests a new delivery system (VitaFlow Liberty Flex) for placing a replacement aortic valve in people with severe aortic stenosis. It is designed for patients whose heart anatomy (a steep angle between the heart and aorta) makes the procedure more challenging.
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