Antibiotic vs. steroid for infected root canals
Part of Mouth & dental clinical trials.
This trial tests two medications placed inside a tooth during root canal retreatment to see which works better at fighting infection. If you need retreatment on a single tooth with an infected root tip area, you may be able to join.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 65 years old.
- You have a tooth that needs retreatment because the area around the root tip is infected (apical periodontitis).
- The infection is in only one tooth, and an X-ray shows it is limited to that tooth.
- You have not taken any antibiotics by mouth in the last 3 months.
- You do not have other health problems that might slow healing or affect your immune system.
- You are not pregnant or breastfeeding.
- You are not allergic to the study medications (calcium hydroxide or betamethasone).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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