New non-opioid painkiller vs usual opioids after ACL surgery
Treatments studied
Part of Pain clinical trials.
This study compares a new non-opioid pain medicine (suzetrigine) with usual opioid painkillers after ACL surgery. It aims to see if it can control pain just as well, without the risks of opioids.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are having surgery to repair a torn ACL (a major knee ligament).
- You do not have other ligament or cartilage injuries in the same knee that need surgery.
- You have not been taking opioid pain medicines (like oxycodone) regularly for a long time before the surgery.
- You are not pregnant or breastfeeding, and if you are a woman of childbearing age, you are not using certain hormonal contraceptives that contain progestins (other than levonorgestrel or norethindrone).
- You do not have severe liver disease (cirrhosis).
- You are able to answer questionnaire on a device (like a phone or tablet) on your own.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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