MR-guided radiation boost for esophageal cancer
Part of Cancer, Digestive system clinical trials.
This trial tests whether giving a higher dose of radiation to the main tumor, guided by MRI scans, can improve treatment for a type of esophageal cancer called squamous cell carcinoma. You would first receive standard chemoradiation followed by surgery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have squamous cell carcinoma of the esophagus or gastroesophageal junction (Siewert type I or II).
- Your tumor is considered locally advanced but can be removed with surgery (stages cT2-3, N0-3, M0).
- You are scheduled to receive chemoradiation (carboplatin, paclitaxel, and 41.4 Gy radiation) followed by surgery.
- Your tumor is 10 cm or shorter.
- You are 18 years or older and have a good performance status (WHO 0-2).
- You are able to have an MRI scan without any contraindications (like certain metal implants or claustrophobia).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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