Personalized vaccine with chemo for new glioblastoma
Treatments studied
Part of Cancer clinical trials.
This trial tests a personalized vaccine (made from your own immune cells and tumor 'neoantigens') combined with the chemotherapy drug temozolomide for people with newly diagnosed glioblastoma. The goal is to see if adding the vaccine helps the immune system better fight the tumor.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 to 75 years old
- You have been newly diagnosed with glioblastoma, and doctors confirmed it's a certain type (IDH wild-type)
- You already had surgery and standard chemoradiotherapy (temozolomide with radiation)
- You are healthy enough to have blood drawn and your organs work well
- You do not have active serious infections or autoimmune disease that requires strong immune-suppressing drugs
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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