Clin2
NCT07371273Possibly a fitRecruiting

Comparing three surgeries for low rectal cancer

Colorectal Cancer

Part of Cancer, Digestive system clinical trials.

This trial tests three different surgical methods for rectal cancer located very close to the anal canal. The goal is to see which method works best in the short and long term while preserving anal function.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
100 people
Ages
18 years to 75 years
Study type
Interventional

Who can take part

  • You have rectal cancer confirmed by a digital exam, colonoscopy, and biopsy.
  • The lower edge of your tumor is between 1.5 and 2.0 cm from the dentate line (a line inside the anal canal).
  • Your anal function is good before surgery (you have good control over bowel movements).
  • The tumor does not go into the muscle layer between the anal sphincters (intersphincteric space).
  • The tumor is smaller than 3 cm long and takes up less than one-third of the bowel's circumference.
  • You are healthy enough for surgery, with an ASA score of 3 or less (a standard measure of surgical risk).

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07346534Enrolling by invitation
Comparing reinforced vs. standard bowel connection in rectal cancer surgery

This study compares two ways of reconnecting the bowel after removing rectal cancer using keyhole surgery. It aims to see if a reinforced connection (with extra support) helps prevent leaks better than the standard method.

Shanghai
NCT06567756Not yet recruiting
Comparing two surgeries for low rectal cancer to preserve bowel control

This trial compares two surgical techniques to remove low rectal cancer while aiming to preserve bowel control. It may help you keep better anal function after surgery.

NCT04098471Recruiting
Comparing two rectal cancer surgeries for T2 tumors

This trial compares two different surgery approaches for early-stage rectal cancer (T2N0M0) that is close to the anus. It tests whether a less invasive local removal followed by radiation works as well as more extensive surgery (total mesorectal excision).

Nanjing, Jiangsu
NCT07849023Recruiting
Precise sphincter-saving surgery for early rectal cancer

This trial tests a refined surgical method for removing rectal tumors while preserving the anal sphincter, which may help avoid a permanent colostomy. It is for patients with early-stage rectal cancer that is close to the anus and has not spread.

Wenzhou, Zhejiang
NCT07651553Recruiting
Transanal vs. Robotic Surgery for Rectal Cancer

This trial compares two surgical approaches to remove rectal cancer while preserving bowel function. Researchers want to see which method—performed through the anus or with robotic assistance—leads to better outcomes and quality of life.

Guangzhou, Guangdong
NCT05964530Recruiting
Testing local removal versus radical surgery for rectal cancer

This trial looks at whether removing the rectal tumor locally (through the anus) can work as well as a more extensive operation after scans show no remaining cancer. It may help some people avoid bigger surgery if the cancer truly appears gone after treatment.

Taipei

Hear when a new Colorectal cancer trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.