Evolocumab for pancreatitis from high triglycerides
Treatments studied
Part of Digestive system, Hormones & metabolism clinical trials.
This trial tests adding evolocumab, a medicine that lowers fats in the blood, to standard treatment for people hospitalized with pancreatitis caused by very high triglycerides. The goal is to see if it helps improve recovery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 75 years old.
- You have acute pancreatitis caused by high triglycerides (HTG-AP).
- You have mixed hyperlipidemia (high levels of multiple blood fats).
- You have not taken evolocumab in the last month before hospital admission.
- You have not received any other lipid-lowering drugs or blood purification therapy before this episode.
- You are not pregnant or breastfeeding, and you have no severe allergies or other life-limiting conditions.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests whether a GLP-1 medication (a drug that helps control blood sugar and triglycerides) can prevent pancreatitis from coming back in people who had a severe attack caused by very high triglyceride levels. If it works, it could help you avoid future painful attacks.
This study looks at people with acute pancreatitis caused by very high blood fat levels (triglycerides). It aims to collect information to better understand and treat this condition.
This trial tests two experimental drugs, HRS-7249 and SHR-1918, to lower very high triglyceride levels in people who are at high risk for pancreatitis. It aims to see if these drugs can reduce the risk of pancreatitis attacks.
This trial tests if adding a probiotic (Bacillus subtilis and Enterococcus faecium) to standard lipid-lowering therapy helps people with mild pancreatitis caused by very high triglycerides. It aims to see if the combination reduces inflammation and speeds recovery.
This Phase 1 trial tests the safety of a gene therapy for people with inherited, hard-to-control high triglycerides (fat in the blood) who have had pancreatitis episodes. It may help by targeting the genes involved in triglyceride control, but the main goal here is to check safety and tolerability.
This trial looks at how severe acute pancreatitis works by using advanced tests on your body's germs, chemicals, and proteins. It may help find better ways to treat patients with this condition.
Hear when a new Hypertriglyceridemia Induced Acute Pancreatitis trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.