Hormone therapy with or without chemo for early breast cancer
Treatments studied
Part of Cancer, Hormones & metabolism clinical trials.
This trial tests whether skipping chemotherapy and using only hormone therapy with a drug called ribociclib works as well as chemotherapy followed by hormone therapy with ribociclib for certain early breast cancers that have a low risk of coming back.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 or older and have had surgery for breast cancer.
- Your cancer is hormone receptor-positive (ER-positive) and HER2-negative, with an Oncotype DX Recurrence Score of 25 or lower.
- You have not had chemotherapy for this cancer before, and you have not taken a CDK4/6 inhibitor before.
- You have no other serious health conditions that could make treatment risky.
- You are postmenopausal or a man.
- Your surgery for breast cancer happened less than 16 weeks before joining the trial.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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