New DNA test for severe epilepsy in children
Part of Brain & nervous system clinical trials.
This trial uses a new, more detailed DNA test (long-read sequencing) to find the cause of severe epilepsy with developmental delays in children when standard genetic testing did not provide an answer. It aims to help families understand the genetic basis of their child's condition.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Your child is under 18 years old.
- Your child has a severe epilepsy with developmental delays (called developmental and epileptic encephalopathy).
- Your child's brain MRI shows no signs of oxygen shortage at birth.
- Your child's standard genetic test (short-read genome sequencing) was negative or unclear.
- You have a stored DNA sample from your child available at a participating hospital.
- You (parent or guardian) are 18 or older, can understand the study, and are willing to sign a consent form.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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