Resistance exercise for transgender women starting estrogen therapy
Part of Brain & nervous system clinical trials.
This study looks at whether resistance training (like lifting weights) can help transgender women and gender-diverse people assigned male at birth who are starting estrogen and testosterone-blocking medications. It aims to see if exercise improves health and well-being.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years old or older.
- You are starting estrogen (pill, under-the-tongue, patch, or injection) AND a testosterone blocker (like spironolactone) as part of your gender-affirming hormone therapy.
- You identify as a transgender woman, transgender female, gender-diverse, non-binary, gender non-conforming, gender-fluid, or gender-queer.
- You were assigned male at birth.
- You do not have a health condition that makes resistance exercise unsafe, such as serious heart or lung problems.
- You have not used testosterone therapy for more than 1 month in the last 6 months.
- You have not taken gender-affirming hormones (estrogen or testosterone blockers) for more than 1 year in the past.
- You have not had surgery to remove your testicles (orchiectomy).
- You currently do less than 60 minutes per week of resistance exercise (like lifting weights, using resistance bands, or bodyweight exercises).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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