Advanced tests for unclear cystic fibrosis diagnosis
Part of Digestive system, Genetic & congenital, Lungs & breathing clinical trials.
This study looks at new, advanced tests to help doctors better diagnose cystic fibrosis in people whose current test results are not clear. Participation involves a rectal biopsy, which helps researchers study how the CFTR protein works in the body.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 16 years old or older.
- You must have a confirmed or unclear diagnosis of cystic fibrosis, or you must not have the condition at all (the study has three different groups).
- You must be willing to undergo a rectal biopsy, which is a small tissue sample taken from your rectum.
- You must not have a bleeding disorder or other condition that makes a rectal biopsy unsafe.
- You must not be pregnant or breastfeeding.
- You must be able to give informed consent, meaning you fully understand and agree to the study.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study looks at how lung infections and inflammation affect people with cystic fibrosis during severe flare-ups. It aims to understand which antibiotics work best and why, so your care team can choose the right treatment for you.
This study tests a new method to detect bacteria in the lungs of people with cystic fibrosis (CF) by analyzing mucus samples. It aims to improve how we diagnose and treat lung infections.
This study tests whether people with cystic fibrosis who are already on a triple combination CFTR modulator can stay on their treatment without interruptions or problems. It aims to make sure everyone gets the best, most consistent treatment for their CF.
This study looks for simple signals (markers) that may show whether cystic fibrosis treatments are working. It includes people who take CF “modulator” medicines like ivacaftor, people who don’t, and people whose cystic fibrosis was ruled out after testing.
This trial tests how well cystic fibrosis (CF) medicine works for you using an “n-of-1” approach, meaning you try treatments in a structured, repeated way to see what helps you most. It may help your care team choose the best option for your specific CF genetics and health status.
This study collects cells from people with cystic fibrosis (CF) caused by rare CFTR gene changes. The goal is to build a cell bank for future research, which may help scientists develop better tests and treatments for rare CF types.
Hear when a new Cystic Fibrosis (CF) trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.