CAR-NK cell therapy plus cetuximab for belly-spread colorectal cancer
Treatments studied
Part of Cancer, Digestive system clinical trials.
This trial tests a new cell therapy (CAR-NK cells given directly into your belly and a vein) combined with a targeted drug (cetuximab) for colorectal cancer that has spread mainly to the lining of your belly. It aims to see if this treatment can shrink tumors and help people who have run out of standard chemotherapy options.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 or older.
- Your cancer must be a type called microsatellite stable (MSS) and not have the BRAF V600E gene change.
- Your tumor spread should mainly be in the lining of your belly, with no more than 8 small tumors elsewhere.
- You must be willing to have a small surgery (diagnostic laparoscopy) to place a catheter in your belly for the treatment.
- You must have adequate heart, kidney, liver, and blood function as checked by your doctor.
- If you could become pregnant or father a child, you must agree to use effective birth control during the study and for 4 months after.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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