Early midodrine for ascites in acute-on-chronic liver failure
Treatments studied
Part of Digestive system clinical trials.
This trial tests whether starting midodrine early can help control or prevent fluid buildup in the belly (ascites) and related problems in people with acute-on-chronic liver failure. If it works, it may reduce the need for more intensive treatments.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 years or older.
- You must have a diagnosis of acute-on-chronic liver failure (a sudden worsening of chronic liver disease).
- You must have moderate to severe fluid buildup in your belly (called ascites, grade 2 or 3).
- You must be willing to follow a low-salt diet, undergo lab tests and urine collections, and attend follow-up visits.
- You must not have certain conditions like severe kidney problems, very low sodium, active infections, or heart issues that make midodrine unsafe.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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