Clin2
NCT07423104Possibly a fitNot yet recruiting

Study of a drug combo for people with relapsed AML

Acute Myeloid Leukemia (AML)

Part of Blood & lymphatic, Cancer clinical trials.

This trial tests a combination of three drugs (cladribine, low-dose cytarabine, and venetoclax) for people with acute myeloid leukemia (AML) that has come back or hasn't responded to treatment, including those who have previously taken venetoclax. The goal is to see if this combo can help control the leukemia.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
24 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are 18 years or older.
  • You have AML that has come back or hasn't responded to treatment, or you have secondary AML that developed from a prior blood disorder (like MDS or MPN).
  • You have already been treated with a venetoclax-containing regimen.
  • Your overall health is fairly good (able to do light activities).
  • Your liver and kidneys are working adequately.
  • If you are able to become pregnant or have a partner who can, you agree to use effective birth control during treatment and for several months after.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07486726Not yet recruiting· Phase 1/Phase 2
Aclarubicin, azacitidine and venetoclax for acute myeloid leukemia

This study tests a combination of three drugs—aclarubicin, azacitidine, and venetoclax—for people with acute myeloid leukemia (AML) who cannot have intensive chemotherapy, or whose leukemia has returned after treatment. The goal is to see if this combination helps control the leukemia with manageable side effects.

Shanghai
NCT06660368Recruiting· Phase 2
A study of a drug combo for relapsed or refractory AML

This trial tests a combination of targeted therapy (venetoclax) and chemotherapy (cladribine, cytarabine, G-CSF, mitoxantrone) for people with acute myeloid leukemia that has come back or not responded to previous treatment. It aims to see if this combination can help achieve remission.

Tampa, Florida
NCT06084819Recruiting· Phase 2
New drug combo for relapsed AML

This trial tests a new drug combination (venetoclax plus CACAG chemotherapy) for people whose acute myeloid leukemia has come back or not responded to earlier treatments. The goal is to see if this combination can help control the leukemia.

Beijing, Beijing Municipality
NCT06763666Not yet recruiting· Phase 4
Adding venetoclax to standard chemo for relapsed AML

This trial tests whether adding a drug called venetoclax to the usual chemotherapy (CLAG) helps people whose acute myeloid leukemia (AML) has come back or not responded to treatment. It aims to see if the combination improves outcomes compared to chemotherapy alone.

Guangzhou, Guangdong
NCT06156579Recruiting· Phase 2
Venetoclax and Decitabine for Relapsed or Refractory AML

This trial tests a combination of two drugs, venetoclax (a pill) and decitabine (given by IV), for people with AML that has not responded to initial treatment or has come back. The goal is to see if this combination can help control the leukemia again.

Tübingen, Baden-Wurttemberg
NCT06232694Recruiting
Combination therapy for newly diagnosed AML

This study tests a combination of two drugs (MDCyta and venetoclax) after an initial treatment to see if it helps people with newly diagnosed AML stay in remission. It is for adults aged 18 to 60 who are otherwise fairly healthy.

Nanjing, Jiangsu

Hear when a new Acute Myeloid Leukemia (AML) trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.