Clin2
NCT07486726Possibly a fitNot yet recruiting

Aclarubicin, azacitidine and venetoclax for acute myeloid leukemia

Acute Myeloid Leukemia (AML)Relapse Acute Myeloid LeukemiaRefractory Acute Myeloid Leukemia (AML)

Treatments studied

Part of Blood & lymphatic, Cancer clinical trials.

This study tests a combination of three drugs—aclarubicin, azacitidine, and venetoclax—for people with acute myeloid leukemia (AML) who cannot have intensive chemotherapy, or whose leukemia has returned after treatment. The goal is to see if this combination helps control the leukemia with manageable side effects.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1/Phase 2
Enrollment
112 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • Be 18 years or older
  • Have acute myeloid leukemia (AML) that is either newly diagnosed and you are not able to get intensive chemo, or that came back after prior intensive chemo
  • Be generally able to care for yourself (ECOG score under 3)
  • Have a white blood cell count below 25 – but hydroxyurea can be used to bring it down
  • Have adequate liver and kidney function
  • Be able to swallow capsules

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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