Aclarubicin, azacitidine, and venetoclax for AML
Treatments studied
Part of Blood & lymphatic, Cancer clinical trials.
This trial tests a combination of three drugs (aclarubicin, azacitidine, and venetoclax) for adults with acute myeloid leukemia (AML) who either cannot have intensive chemotherapy or whose AML has come back after treatment. The goal is to see if this combination is safe and works better.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You have AML that is either newly diagnosed and you cannot have intensive chemo, or it has returned after previous treatment.
- Your white blood cell count is below a certain level (can be lowered with hydroxyurea first).
- Your liver and kidney function are adequate (simple blood tests can check).
- You are able to swallow pills.
- If you are of childbearing age, you agree to use effective birth control during and for 6 months after treatment.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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