Timing of stem cell booster for healthy donors
Treatments studied
This trial tests whether giving a stem cell-mobilizing medicine (G-CSF) at a specific time of day based on your natural sleep/wake rhythm can improve the collection of blood stem cells from healthy donors. It aims to make the donation process more efficient and comfortable.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be between 18 and 55 years old.
- You should be a healthy donor, matching the person who will receive your stem cells.
- Your weight must be at least 35 kg (about 77 pounds), and you need enough blood volume for the collection process.
- You must have a regular sleep/wake schedule (no night shifts or long-distance travel across time zones recently).
- You cannot have serious health problems like blood disorders, heart disease, or autoimmune conditions.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This Phase 3 study tests using filgrastim (a medicine that helps stem cells leave the bone marrow) to collect stem cells from unrelated donors for transplant. It focuses on donor safety and whether this collection method works well enough for transplantation.
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This early (Phase 1) study tests whether giving a growth factor injection (rhu-G-CSF) to healthy volunteers can help collect whole blood for research. It looks at safety and whether the donated blood can be collected under specific health conditions.
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