Clin2
NCT06294691Possibly a fitRecruiting

Timing of stem cell infusion to prevent GVHD in blood cancer

Acute Graft-versus-host Disease

Part of Immune system & allergy clinical trials.

This study is testing whether the timing of a stem cell infusion affects the chance of developing graft-versus-host disease (aGVHD), a common complication after transplant. It may help make transplants safer for people with blood cancers.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
198 people
Ages
12 years to 60 years
Study type
Interventional

Who can take part

  • You must be between 12 and 60 years old.
  • You must have a confirmed malignant blood disease (like leukemia) and be planning your first stem cell transplant from a donor.
  • You should be in fairly good health with no major organ failure or active infections.
  • You must be willing to take part in a study where the timing of the stem cell infusion is randomized, and you can sign a consent form.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07047456Recruiting· Phase 3
Stem cell infusion timing and graft-versus-host disease risk in blood cancer patients

This trial looks at whether the time when stem cells are infused affects the chance of developing graft-versus-host disease (aGVHD) after a cord blood transplant. It may help find the best timing to improve outcomes for people with blood cancers.

Hefei, Anhui
NCT06949267Not yet recruiting· Early Phase 1
Stem cell therapy to prevent graft-versus-host disease after transplant

This study tests whether an experimental cell therapy called iMSC can help prevent graft-versus-host disease (a common complication after a stem cell transplant). It is given soon after your transplant, within 5 days of enrolling, and aims to reduce the chance of this serious condition.

NCT06462365Recruiting· Phase 1
Preventing GvHD after stem cell transplant for blood cancers

This trial tests a new way to prevent graft-versus-host disease (GvHD), a common complication after a stem cell transplant. It is for people with certain blood cancers who are getting a stem cell transplant from a half-matched family member or unrelated donor.

Duarte, California
NCT06756152Recruiting· Phase 2/Phase 3
Preventing GVHD after transplant for blood cancers in children and young adults

This trial tests a combination of four medicines (cyclophosphamide, abatacept, vedolizumab, and ruxolitinib) to prevent graft-versus-host disease (GVHD) after a stem cell transplant for children and young adults with certain blood cancers. The goal is to see if this approach reduces the risk of GVHD, a serious complication where donor cells attack the body.

Moscow
NCT03970096Recruiting· Phase 2
Reduce graft-versus-host disease after stem cell transplant

This Phase 2 study tests ways to lower the risk of graft-versus-host disease (GVHD), a serious complication after an allogeneic stem cell transplant from a matched donor. It is for people with acute leukemia or MDS who are going to receive intensive conditioning therapy, aiming to improve safety while keeping the transplant effective.

Tampa, Florida
NCT06815003Recruiting· Phase 2
Preventing Graft-Versus-Host Disease After Stem Cell Transplant

This trial tests a combination of three drugs (vedolizumab, cyclophosphamide, and tacrolimus) to prevent graft-versus-host disease, a common complication after a donor stem cell transplant. It is for people with certain blood cancers who are getting a reduced-intensity transplant.

Duarte, California

Hear when a new Acute Graft Versus Host Disease trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.