Pain relief options after keyhole thymectomy for myasthenia gravis
Treatments studied
Part of Pain clinical trials.
This trial tests whether adding dexmedetomidine or dexamethasone to the standard numbing medicine (bupivacaine) in a nerve block reduces pain after thymectomy surgery in myasthenia gravis patients. It aims to improve pain relief and recovery after keyhole chest surgery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Diagnosed with myasthenia gravis
- Classified as ASA physical status 2 or 3 (mild to severe but not life-threatening systemic disease)
- Undergoing video-assisted thoracoscopic thymectomy (keyhole surgery to remove the thymus)
- No known allergy to the study drugs (dexmedetomidine, dexamethasone, or bupivacaine)
- No contraindications to the block, such as infection at the site or severe chest deformity
- No significant bleeding disorders, kidney or liver issues, heart block, poor lung function, severe COPD, morbid obesity, or difficulties with pain assessment
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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