Clin2
NCT07432022Possibly a fitNot yet recruiting

EMB-07 combo for aggressive B-cell lymphoma

Combination TherapyAggressive B-Cell Non-Hodgkin LymphomaEMB07phaseI/II

Part of Blood & lymphatic, Cancer clinical trials.

This trial tests a new combination treatment for people with aggressive B-cell non-Hodgkin lymphoma, including those with relapsed/refractory disease or newly diagnosed high-risk cases. It aims to see if EMB-07 combined with other drugs is safe and effective.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1/Phase 2
Enrollment
115 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You must be 18 years or older.
  • Your overall health should be good enough to carry out daily activities with little help (ECOG score 0-1 or 0-2, depending on the phase).
  • You must have a type of aggressive B-cell lymphoma, such as diffuse large B-cell lymphoma (DLBCL) or transformed follicular lymphoma that has come back or not responded to treatment (for Cohort A) or is newly diagnosed with certain risk features (for Cohort B).
  • You cannot have active brain or spinal cord involvement from your lymphoma.
  • You must not have had certain prior treatments that could interfere with the study drugs.
  • Your heart, liver, and kidney function must be adequate, and you must not have serious infections or other uncontrolled medical conditions.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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