Study of AP-472 with levodopa for Parkinson's motor fluctuations
Part of Brain & nervous system clinical trials.
This trial tests an experimental drug called AP-472, taken alongside your regular Parkinson's medications, to see if it can reduce the amount of "OFF" time you experience each day when symptoms return between doses of levodopa.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 30 and 80 years old.
- You have been diagnosed with typical Parkinson's disease (not other forms of parkinsonism).
- You experience at least 3 hours of "OFF" time per day when Parkinson's symptoms return.
- You are able to walk on your own or with a walking aid.
- You have been on a stable dose of your Parkinson's medications for at least 4 weeks, and MAO-B inhibitors for 12 weeks.
- You take levodopa at least 4 times a day for immediate-release or 3 times a day for extended-release formulations.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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