Clin2
NCT07433413Possibly a fitNot yet recruiting

Implanted medicine for alcohol use disorder

Alcohol Use Disorder (AUD)

Treatments studied

Part of Mental health clinical trials.

This study tests a small implant that slowly releases naltrexone, a medicine that helps reduce alcohol cravings. It may help people with alcohol use disorder stay sober, and the implant offers a long-acting option that doesn't require daily pills.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
240 people
Ages
18 years to 65 years
Study type
Interventional

Who can take part

  • You must have been diagnosed with moderate to severe alcohol use disorder (meeting 4 or more DSM-5 criteria).
  • You must not be pregnant, planning pregnancy, or breastfeeding. If you are a woman who can become pregnant, you will need to use effective birth control.
  • You must have normal liver function (no severe liver problems or ultrasound abnormalities that could interfere with the study).
  • You must not have a history of severe pancreatitis or severe alcohol withdrawal seizures (delirium tremens).
  • You must not have used non-alcohol, non-tobacco drugs (like opioids, benzodiazepines, or cocaine) in the past year.
  • You must not have taken naltrexone or received psychological support therapy for alcohol relapse within the past 30 days.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT05408247Recruiting· Phase 4
N-acetylcysteine to help people cut back on alcohol

This trial tests whether N-acetylcysteine (a supplement-like medicine) can help people with alcohol use disorder reduce or stop drinking. You may be randomly assigned to receive N-acetylcysteine or a comparison treatment, and you’ll complete interviews during the study.

Sydney, New South Wales
NCT05028062Recruiting· Phase 4
Naltrexone injections for people who want to cut alcohol drinking

This Phase 4 study tests whether naltrexone injections can help people with alcohol use disorder (AUD) reduce or stop heavy drinking. You may get two injections over 8 weeks, and you can join if you meet specific drinking pattern and eligibility rules.

Philadelphia, Pennsylvania
NCT07249554Not yet recruiting· Phase 2
Combination medications for alcohol use disorder

This study tests whether combining two medications—one that helps control cravings and one that affects appetite and reward—can help people reduce or stop drinking alcohol. If you are in treatment for alcohol use disorder收, this may offer a new way to support your recovery.

Havre de Grace, Maryland
NCT05382091Not yet recruiting· Phase 2
Naltrexone implant for opioid relapse prevention

This study tests a long-acting implant that releases naltrexone slowly over time to help prevent relapse in people with opioid use disorder. The implant is placed under the skin in a minor procedure and may help you stay opioid-free.

NCT07269873Recruiting· Phase 1
Testing a new implant for opioid use disorder

This study tests a new implant (BICX104) with or without bupropion to see how safe it is and how it works in the body, compared to an existing treatment (Vivitrol). If you are healthy and not using opioids, you may be eligible to help researchers understand if this implant could be a new option for treatment.

Miami, Florida
NCT06622239Not yet recruiting· Phase 2
Naltrexone for reducing self-injury

This study tests whether a medication called naltrexone can help reduce the urge or behavior of self-injury (hurting yourself on purpose) in people who have not improved with standard treatment. It may offer a new option to manage these urges.

Seoul

Hear when a new Alcohol Use Disorder (AUD) trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.