Testing a new implant for opioid use disorder
Treatments studied
Part of Mental health clinical trials.
This study tests a new implant (BICX104) with or without bupropion to see how safe it is and how it works in the body, compared to an existing treatment (Vivitrol). If you are healthy and not using opioids, you may be eligible to help researchers understand if this implant could be a new option for treatment.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 65 years old.
- You are in good health as determined by a doctor (based on medical history, physical exam, and lab tests).
- You are not currently using opioids and have a negative urine drug test.
- Your body mass index (BMI) is between 18.5 and 30.
- You agree to use effective birth control if you could become pregnant.
- You have no history of seizures, certain heart conditions, or psychiatric disorders with suicidal thoughts.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests a long-acting implant that releases naltrexone slowly over time to help prevent relapse in people with opioid use disorder. The implant is placed under the skin in a minor procedure and may help you stay opioid-free.
This study tests a small implant that slowly releases naltrexone, a medicine that helps reduce alcohol cravings. It may help people with alcohol use disorder stay sober, and the implant offers a long-acting option that doesn't require daily pills.
This study tests whether a medication called naltrexone can help reduce the urge or behavior of self-injury (hurting yourself on purpose) in people who have not improved with standard treatment. It may offer a new option to manage these urges.
This trial tests whether a combination of buprenorphine (through your care plan) and a monthly extended-release naltrexone (XR-NTX) shot can help prevent opioid relapse. It may help people who are ready to move toward a naltrexone-based relapse-prevention treatment after detox.
This trial tests whether a single treatment with ibogaine, a plant-based medicine, combined with a year of app and wearable support, helps people reduce or stop opioid use. It is for adults who have not had success with other treatments and are seeking a new option.
This study tests whether the medication naltrexone can help reduce self-harm urges or actions in people who hurt themselves without intending suicide. It may offer a new option if current treatments haven't been enough.
Hear when a new Healthy Adult Male and Female Volunteers trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.