Ultrasound to monitor sarcoma response to radiation
Treatments studied
Part of Cancer clinical trials.
This trial uses contrast-enhanced ultrasound to see how well soft tissue sarcoma responds to radiation therapy given before surgery. The goal is to find out if this imaging method can help doctors assess treatment effects earlier.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have been diagnosed with soft tissue sarcoma in your trunk or an arm or leg
- You are scheduled to receive radiation therapy before surgery for your sarcoma
- You are 18 years of age or older
- You are willing to follow all study procedures and attend visits
- Your sarcoma is not too large for ultrasound (shorter side no bigger than 10 cm at 2 cm depth)
- You do not have other cancers needing active treatment, metastatic disease, or prior radiation to the same area
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This trial tests a non-surgical ultrasound treatment (HIFU) that targets the tumor from the outside of the body. It may help by shrinking or controlling certain types of soft tissue sarcoma or desmoid tumors when they are hard to remove surgically or when surgery/chemo/radiation is not a good option.
This study tests a 5-day course of radiation before surgery instead of the usual 5 weeks. It may help people who face challenges like travel or tumor growth that make the longer schedule difficult.
This trial tests a newer way of giving radiation (spatially fractionated) compared to standard radiation for people with large soft tissue sarcomas. It aims to see if the new method works better.
This trial tests a personalized (“adaptive”) radiation plan before surgery for high-grade soft-tissue sarcoma that can be removed. It may help shrink the tumor and improve how well surgery can treat the cancer.
This trial tests a new type of radiation called spatially fractionated radiation therapy (SFRT) given before surgery for large soft tissue sarcomas in the arm, leg, or trunk. The goal is to see if it helps shrink the tumor and improve treatment outcomes.
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