Steroid implant plus aflibercept for diabetic macular edema
Part of Eyes & vision clinical trials.
This trial tests whether combining a steroid implant (dexamethasone) with an anti-VEGF injection (aflibercept) works better than the injection alone for people with diabetic macular edema who haven't been treated yet. It aims to improve vision and reduce retinal swelling.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are age 18 or older and have type 1 or type 2 diabetes
- Your diabetes is under good control (A1C is 10% or lower)
- You have diabetic macular edema affecting the center of your vision, with the retina thickness at least 300 microns measured in the central 1 mm area
- You have never had any prior treatment for diabetic macular edema in the study eye (like anti-VEGF injections or steroid implants)
- You must not have severe cataracts, other macular conditions, or a history of eye surgery that might interfere with the study
- You are not pregnant, lactating, or allergic to the study drugs
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests a treatment for diabetic macular edema (swelling in the back of the eye caused by diabetes) in people who have not had eye injections before. It aims to see if the treatment can improve vision.
This trial tests a high-dose version of the drug aflibercept (given as an eye injection) for people with diabetic macular edema who have previously had a vitrectomy surgery. The goal is to see if this higher dose can help reduce swelling and improve vision.
This study tests whether a steroid medication can help reduce swelling in the back of the eye caused by diabetic macular edema, a complication of type 2 diabetes. If you qualify, you may receive this treatment to potentially improve your vision.
This trial tests an eye injection called OLN324 for diabetic macular edema, a condition where fluid builds up in the retina and blurs vision. The treatment aims to improve vision and reduce swelling in the eye.
This study tests whether one eye injection (aflibercept) works better than another (bevacizumab) for people with diabetic macular edema. Both are already used for this condition, and the goal is to see which provides better vision improvement.
This study tests an experimental eye injection (OLN324) for people with diabetic macular edema, a condition where swelling in the back of the eye causes vision loss. The goal is to see if the injection can improve vision.
Hear when a new Diabetic Macular Edema (DME) trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.