Clin2
NCT07444775Possibly a fitRecruiting

Comparing two radiation methods for pain from large tumors

Histopathologically or Cytologically Confirmed Solid Tumor Who Require Palliation Radiation Therapy to a Lesion ≥5cm

Part of Cancer clinical trials.

This trial compares two types of radiation therapy — lattice and conventional — to find which is better at reducing pain from large tumors that cannot be surgically removed. You'll also receive standard pain management, and the study helps decide if the newer lattice technique is more effective with fewer side effects.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
148 people
Ages
18 years to 99 years
Study type
Interventional

Who can take part

  • You must have a solid tumor (not a blood cancer) that is larger than 5 centimeters (about 2 inches) and is not able to be removed with surgery or treated with standard radiation alone.
  • In the past 24 hours, your worst pain must be at least a 2 on a 0–10 scale.
  • You must be well enough to have any level of daily activity, from fully active to bedridden (ECOG 0–4).
  • You must be willing to fill out pain questionnaires and keep a pain diary before and after treatment.
  • You cannot be pregnant or planning to have children within 90 days of the trial.
  • You must not have had radiation to the same area before, or have a condition like a connective tissue disorder that would make radiation unsafe.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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